Neural oscillatory basis of functional connectivity MRI differences between semantic word tasks

versus-concrete word processing [5] found left temporal and operc/tri frontal activity greater for abstract-words and left fusiform, parietal/occipital junction and mid-occipital for concrete-words; this is consistent with the findings here: in theta (SupPar with InfTemp) and in beta-gamma (left orbital frontal with left operc/tri frontal and mid-occipital). Other areas were also found to be different between conditions that were not found in the meta-analysis above; however, this is exciting as the meta-analysis only focussed on unimodal fMRI task-changes, not connectivity changes, nor haemodynamic changes in relation to neural oscillations. This study not only illustrates how multi-imaging-modality whole-brain functional connectivity changes can be used to understand semantic word processing from a spatial-spectral view, but also demonstrates the importance and ability of multimodal fMRI/MEG studies for connectivity. References: [1] Payne et al. 2009 Brain Res. 1247:126-32 [2] Shinkareva et al. 2009; NeuroImage, V 47, Suppl. 1, Page S147 [3] Brookes et al. 2010 Biomag; Dubrovnik [4] Tzourio-Mazoyer et al., 2002. NeuroImage 15:273-289 [5] Wang et al. Accepted. HBM. Proc. Intl. Soc. Mag. Reson. Med. 18 (2010) 3516